PUblications

Publications

Congress Presentation
April 9, 2024
AACR 2024

Analytical performance of a genome-wide methylome enrichment platform to detect minimal residual disease from plasma-derived cell-free DNA

Congress Presentation
April 8, 2024
AACR 2024

The development of a tissue-agnostic genome-wide methylome enrichment MRD assay for applications across the cancer care continuum for head and neck malignancies

Publication
February 23, 2024
Cancer Discovery

Early Changes in Tumor-Naive Cell-Free Methylomes and Fragmentomes Predict Outcomes in Pembrolizumab-Treated Solid Tumors

Congress Presentation
November 30, 2023
MTCS 2023

Prognostic Performance of a Genome-Wide Methylome Enrichment Platform in Early-Stage Non-Small Cell Lung Cancer (NSCLC)

Congress Presentation
November 14, 2023
AMP 2023

Pre-Analytic Variables and Quality Controls for Robust Processing of Plasma-Derived Cell-Free DNA (cfDNA) Using a Whole Methylome Enrichment Platform

Congress Presentation
October 21, 2023
ESMO 2023

Prognostic Performance of a Genome-Wide Methylome Enrichment Platform in Head and Neck Cancer

Congress Presentation
October 21, 2023
ESMO 2023

Evaluation of a Genome-Wide Methylome Enrichment Platform for Circulating Tumor DNA Quantification and Prognostic Performance in Renal Cell Carcinoma (RCC)

Congress Presentation
April 16, 2023
AACR 2023

Development of a Genome-Wide Methylome Enrichment Platform for Multi-Cancer Early Detection

Publication
December 22, 2022
iScience

Cell-free DNA methylation-defined prognostic subgroups in small-cell lung cancer identified by leukocyte methylation subtraction

Publication
December 1, 2022
Neuro-Oncology

Cerebrospinal fluid methylome-based liquid biopsies for accurate malignant brain neoplasm classification

Publication
October 29, 2022
Nature Communications

The cell-free DNA methylome captures distinctions between localized and metastatic prostate tumors

Publication
September 9, 2022
Cell Reports Methods

Sensitive and reproducible cell-free methylome quantification with synthetic spike-in controls

Publication
August 1, 2021
Clin Cancer Res 27 (15): pg. 230–4244 (2021)

Tumor-Naïve Multimodal Profiling of Circulating Tumor DNA in Head and Neck Squamous Cell Carcinoma

Publication
June 22, 2020
Nature Medicine 26, pg. 1041–1043 (2020)

Detection of renal cell carcinoma using plasma and urine cell-free DNA methylomes

Publication
June 22, 2020
Nature Medicine 26, pg. 1044–1047 (2020)

Detection and discrimination of intracranial tumors using plasma cell-free DNA methylomes

Publication
August 30, 2019
Nature Protocols 14, pg. 2749–2780 (2019)

Preparation of cfMeDIP-seq libraries for methylome profiling of plasma cell-free DNA

Publication
November 14, 2018
Nature 563, pg. 579–583 (2018)

Sensitive tumour detection and classification using plasma cell-free DNA methylomes